Pathogen adaptation has contributed to the resurgence of pertussis. To facilitate our understanding of this adaptation we report here 11 completely closed and annotated Bordetella pertussis genomes representing the pandemic ptxP3 lineage. Our analyses included six strains which do not produce the vaccine components pertactin and/or filamentous hemagglutinin.
Authors:Bart MJ1, van der Heide HG2, Zeddeman A1, Heuvelman K2, van Gent M3, Mooi FR1.
Journal:Genome Announc. 2015