Severe Neonatal Pertussis Treated by Leukodepletion and Early Extra Corporeal Membrane Oxygenation.

We report the case of a 17-day-old infant with severe pertussis for whom the early initiation of veno-arterial extra corporeal membrane oxygenation andleukodepletion strategies (exchange transfusion andleukofiltration)allowed to reduce leukocytosis and pulmonary hypertension, thus leading to survival. These invasive techniques can be considered when severe pulmonary hypertension complicates hyperleukocytosis in neonates.

Authors:Assy J1, Séguéla PE, Guillet E, Mauriat P.
Journal:Pediatr Infect Dis J. 2015
Link:http://www.ncbi.nlm.nih.gov/pubmed/26090571