Pertussis Resurgence Associated with Pertactin-Deficient and Genetically Divergent Bordetella Pertussis Isolates in Israel.

The Bordetella pertussis polymerase chain reaction positivity rate changed after additional diphtheria-tetanus-acellular-pertussis boosters in 2005 and 2008, 9.8%, 13.4%, 22% and 15.2% in 2010, 2011, 2012 and 2013, p<0.001, respectively. New pulsed-field gel electrophoresis profiles were detected between 2009 and 2012. The proportion of pertactin-deficient isolates increased over time, 6.6% vs. 7.1% vs. 33.3% during 2005-2006, 2011-2012 and 2013-2014, p<0.03.

Authors:Bamberger E1, Raya BA, Cohen L, Golan-Shany O, Davidson S, Geffen Y, Srugo I.
Journal:Pediatr Infect Dis J. 2015
Link:http://www.ncbi.nlm.nih.gov/pubmed/25966915