Whither pertussis?

Several lines of evidence suggest that pertussis disease will continue to rise in countries which have switched to acellular vaccines. While maternal vaccination is promising as a mitigating strategy it is unlikely to replace the need for a better vaccine. In the absence of a clear alternative, a return to using whole cell vaccines, at least in part, should not be dismissed as an option without contemporary studies of feasibility and acceptability.

 

Authors:Snelling TL1, Waddington CS.

Journal:Expert Rev Anti Infect Ther. 2014

Link:http://www.ncbi.nlm.nih.gov/pubmed/25426699